Found 10 matching trials
To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Patients With Hepatic Impairment and Healthy Subjects PHASE1 A study to assess the pharmacokinetics, safety and tolerability of Selumeti...
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Selumetinib in Combination With Gefitinib in NSCLC Patients PHASE1 This is an open-label, non-randomized, multicenter phase Ib/II study, which...
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National Cheng Kung University Hospital
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Mitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in People With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST) PHASE2 Background:
Gastrointestinal stromal tumors (GIST) can cause serious medic...
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Multiple Locations
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To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Renal Impaired Subjects and Healthy Subjects PHASE1 A study to assess the pharmacokinetics, safety and tolerability of Selumeti...
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SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors PHASE2 To determine the clinical benefit rate of selumetinib in combination with s...
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Children's National Medical Center
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Selumetinib (AZD6244, ARRY-142886) J-BTC Phase 1 Study PHASE1 The objective of this study is to investigate the safety and tolerability o...
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AZD6244 PhI Japanese Gem/
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Dual REctcal Angiogenesis or MEK Inhibition radioTHERAPY Trial PHASE1 To determine the maximum tolerated dose (MTD) of AZD6244 or AZD2171 when co...
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The Christie NHS Foundation Trust
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The Clinical Study of the Treatment of Patients With Type I Neurofibromatosis With Smetinib Hydrosulfate Capsule PHASE2 This study focused on patients with type I neurofibromatosis undergoing sur...
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Multiple Locations
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A Study of Selumetinib in Patients With Kaposi's Sarcoma PHASE1 Cancer is a leading cause of death in individuals living with human immunod...
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Brighton and Sussex University Hospitals
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Clinical Study on the Treatment of Type I Neurofibromatosis With Smeitinib Hydrosulfate Capsule PHASE2 This study focused on patients with type I neurofibromatosis, who currently...
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Multiple Locations
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